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08.09.2026

Sangrovit®: three decades of innovation, from pioneering phytogenics to 3rd Generation with carcass value

How a botanical feed additive that gained industry recognition in the 1990s has evolved into a modern platform for resilience, feed efficiency, and measurable value at slaughter.
 
Poultry Sangrovit Science & Research

A Success story that began before phytogenics became mainstream

Long before phytogenic feed additives became a major category in animal nutrition, Sangrovit® was already attracting attention from producers, nutritionists, veterinarians, and industry media. Throughout the late 1990s, numerous trade publications reported improvements in animal performance, feed utilization, and profitability associated with Sangrovit® supplementation.

At the time, livestock producers faced a growing challenge. Markets demanded efficient, profitable production while the industry was actively searching for alternatives to traditional antibiotic growth promoters. Sangrovit® offered a different approach: harnessing the power of bioactive compounds from the plant Macleaya cordata to support animal performance naturally.

More than 25 years later, the core promise remains unchanged. What has changed is the science, standardization, and value proposition behind the product.

Today, Sangrovit® has evolved into its 3rd Generation, combining decades of practical experience with advanced plant breeding, patented innovation, and a broader economic impact that extends all the way to carcass quality and meat yield.

The image shows Dr. Hermann Roth, founder of Phytobiotics, standing in a field of Macleaya cordata, returning to the very origin of the product that shaped the company he founded.
 

The early years: practical results that captured industry attention

The historical press collection Pressestimmen (2001) documents how Sangrovit® was perceived across the livestock industry between 1996 and 2001.

Publications consistently highlighted benefits such as:

  • Improved daily weight gain
  • Better feed conversion efficiency
  • Enhanced appetite and feed intake
  • Improved protein utilization
  • Positive economic returns per animal
  • A plant-based alternative to conventional growth-promoting approaches
These reports were particularly noteworthy because they focused on outcomes that mattered most to producers: performance and profitability.
 

Historical economic benefits in today's currency

When the originally reported Deutsche Mark values are converted using the official fixed exchange rate of 1 EUR = 1.95583 DM, the economic advantage reported in the trade press corresponds to approximately €2.28 to €3.67 per finishing pig.
 

Publication Topic reported Benefit (DM) Benefit (EUR)
DGS Magazin 40/1998 Natural improvement of finishing performance 7.18 €3.67
DGS Magazin 22/1999 Alternative feed additives in practice 4.50 €2.30
Mühle und Mischfuttertechnik 7/1997 Performance and ecological benefits 4.46 €2.28
SUS 1/1998 Digestive support under practical conditions 4.50 €2.30
SUS 6/1998 Evaluation of plant-based feed additives 6.25 €3.20
SUS 2/1997 Results from Danish finishing pigs 6.25 €3.20
Deutsche Tierärztliche Wochenschrift 11/1997 Alternative to antibiotic growth promoters 4.50 €2.30

These figures illustrate that Sangrovit®'s value proposition was already built on a measurable return on investment from the very beginning.
 

Building on a proven foundation

For many years, Sangrovit®'s success was linked to its standardized content of bioactive isoquinoline alkaloids derived from Macleaya cordata.

These alkaloids became known for supporting:

  • Consistent feed intake
  • Efficient nutrient utilization
  • Animal robustness during challenging periods
  • Production performance across multiple species
As research expanded and agricultural production systems became increasingly focused on efficiency, sustainability, and welfare, expectations for feed additives also evolved.
The question was no longer simply:
"Can a feed additive help animals grow?"

The question became:
"Can it create value throughout the entire production chain?"

This challenge laid the foundation for the next chapter in Sangrovit®'s evolution.
 

Enter Sangrovit® 3rd Generation

The most significant innovation in recent years has been the introduction of Sangrovit® 3rd Generation, representing the next step in the product's development.

At the center of this advancement is the addition of a fifth standardized alkaloid:

Canadine: expanding the value proposition
Historically, Sangrovit®'s activity was associated with four major isoquinoline alkaloids:

  • Sanguinarine
  • Chelerythrine
  • Protopine
  • Allocryptopine
Sangrovit® 3rd Generation adds:
  • Canadine
This innovation transforms the traditional alkaloid profile into what is now referred to as the "Effective Five." Rather than simply increasing the number of active compounds, the inclusion of canadine broadens the biological and economic relevance of Sangrovit®.

Recent data associate canadine with:
  • Muscle development and protection
  • Antioxidant activity
  • Improved carcass composition
  • Enhanced meat-value parameters
As a result, Sangrovit®'s contribution can now be evaluated not only in terms of feed efficiency and growth performance, but also in terms of what producers deliver to the slaughterhouse.
 

A decade of natural plant breeding

The introduction of standardized canadine was not achieved through chemical manipulation or synthetic technology.
Instead, it was the result of a dedicated natural breeding program for Macleaya cordata conducted in cooperation with a German plant breeding institute.

Key milestones
2012-2022

  • Natural breeding program established to increase canadine levels
2024
  • Commercial rollout announced
End of 2025
  • Sangrovit® 3rd Generation becomes available for sales
2026
  • Product specifications updated to reflect increased active alkaloid concentrations
  • European patent relating to the canadine innovation granted
This combination of natural breeding, standardization, and proprietary technology strengthens Sangrovit®'s position as a differentiated phytogenic solution in global animal nutrition

Beyond performance: delivering more value at slaughter

Perhaps the most exciting development of Sangrovit® 3rd Generation is the emergence of measurable carcass-quality benefits.
While traditional feed additive evaluations often end at feed conversion and body weight gain, newer data demonstrate effects that continue through to processing and meat production.
 

Results in pigs

A study involving 995 PIC pigs supplemented for the final 30 days before slaughter reported:

  • 10.3% lower backfat thickness
  • 2.5% higher lean meat percentage
  • 2.4% larger loin area
  • 2.2% larger rib area
For producers and processors alike, these changes represent a shift from performance value to carcass value.
The implications extend directly into carcass grading, saleable yield, and overall production economics.

 

Results in broilers

A slaughter analysis involving 26,400 Cobb 500 broilers demonstrated improvements in commercially valuable cuts:

  • 2% higher breast meat yield
  • 5% higher inner filet yield
  • 28% lower intraperitoneal fat
Additional observations included:
  • More protein in breast meat
  • Improved water-holding capacity
  • Reduced cooking losses
For the poultry industry, these parameters are particularly relevant because profitability increasingly depends on maximizing high-value cuts while reducing excess fat deposition.

Performance under commercial stress conditions

Modern livestock production rarely occurs under ideal circumstances. Heat stress, environmental fluctuations, and management challenges can significantly impact productivity.
To evaluate Sangrovit® 3rd Generation under practical pressure, the Agricultural University of Athens and FeedIT conducted a broiler trial in 2026 using:

  • 468 Ross 308 broilers
  • Controlled heat-challenge conditions
  • Temperatures elevated 7-8°C above recommendations for seven hours daily during day 36 to 39 of life

Reported Outcomes

Compared with control groups, Sangrovit® 3rd Generation demonstrated:

  • Higher body-weight gain during the heat challenge
  • Improved feed conversion ratio
  • Higher European Production Efficiency Factor
These findings reinforce an increasingly important concept in modern animal production: Resilience. Maintaining predictable performance during periods of stress may be as valuable as maximizing performance under ideal conditions.
 

From Feed Additive to Value Platform

The story of Sangrovit® today is very different from the story told in trade journals 25 years ago.
In the late 1990s, the focus was on growth, feed efficiency, and profitability.
Today, those benefits remain relevant, but Sangrovit®'s value proposition has expanded considerably.
It now combines:

  • Proven production performance
  • Support for feed intake and efficiency
  • Resilience during challenging conditions
  • Standardized five-alkaloid technology
  • Improved carcass composition
  • Enhanced meat-value parameters
  • Potential downstream benefits for processors and integrated production systems

The next chapter

Looking back, the historical press reports were early indicators of a product that would continue evolving for decades. What started as a pioneering phytogenic feed additive has become a science-driven technology platform supported by natural breeding, advanced standardization, and modern production objectives.

The strongest conclusion is simple: Sangrovit® 3rd Generation preserves the proven production benefits of the original platform while adding measurable value at slaughter, creating opportunities for producers, processors, and integrated supply chains alike.
 

About the author

Verena Determann holds a Bachelor of Science in Agricultural Economics from the University of Applied Sciences in Bingen and subsequently deepened her expertise through a Master’s degree in Livestock Sciences at Justus Liebig University Giessen. Nowadays, Verena serves as the Product Manager for Sangrovit® at Phytobiotics. 

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